| University of Chicago Law School | law school | Chicago | 1902 |
| University of Chicago Press | book publisher, university press | Chicago | 1891 |
| University of Colorado Boulder | research university, public educational institution of the United States, public university | — | 1876 |
| University of Colorado Denver | public educational institution of the United States, public university | — | 1912 |
| University of Dayton | private not-for-profit educational institution, university | — | 1850 |
| University of Delaware | public educational institution of the United States, land-grant university, public university | Newark | 1743 |
| University of Denver | research university, private not-for-profit educational institution, private university | Denver | 1864 |
| University of Evansville | private not-for-profit educational institution | Evansville | 1854 |
| University of Guam | university, land-grant university | — | 1952 |
| University of Hawaii Press | open-access publisher, university press | Honolulu | 1947 |
| University of Hawaiʻi–West Oʻahu | public educational institution of the United States, university | Kapolei | 1976 |
| University of Illinois Springfield | public educational institution of the United States, university | — | 1969 |
| University of Kansas | publishing house, public educational institution of the United States, university, open-access publisher, public research university | — | March 21, 1864 |
| University of Kentucky | public educational institution of the United States, open-access publisher, land-grant university, public university | Lexington | 1865 |
| University of Louisiana at Lafayette | public educational institution of the United States, university | Lafayette | 1900 |
| University of Louisville | public educational institution of the United States, public research university | Louisville | 1798 |
| University of Massachusetts | state university system | Boston | 1863 |
| University of Massachusetts Boston | public educational institution of the United States, university | Dorchester | 1964 |
| University of Massachusetts Lowell | public educational institution of the United States, public university | Lowell | 1975 |
| University of Memphis | public educational institution of the United States, public research university | — | 1912 |
| University of Michigan–Flint | public educational institution of the United States, university | — | 1956 |
| University of Minnesota Duluth | public educational institution of the United States, public university | — | 1895 |
| University of Missouri–Kansas City | public educational institution of the United States, public university | — | 1933 |
| University of Montana | research university, public educational institution of the United States, public university | — | 1893 |
| University of Nebraska Omaha | public educational institution of the United States, public university | — | 1908 |
| University of North Alabama | public educational institution of the United States, public university | — | 1830 |
| University of North Carolina at Asheville | liberal arts college, public educational institution of the United States | Asheville | 1927 |
| University of North Carolina at Chapel Hill | public educational institution of the United States, public research university | — | December 11, 1789 |
| University of North Carolina at Charlotte | public educational institution of the United States, public research university | — | 1946 |
| University of North Carolina at Greensboro | public educational institution of the United States, university, open-access publisher | Greensboro | 1891 |
| University of North Carolina Press | nonprofit organization, open-access publisher, university press | Chapel Hill | 1922 |
| University of North Texas | public educational institution of the United States, public research university | Denton | 1890 |
| University of Notre Dame | private not-for-profit educational institution, open-access publisher, Catholic university, private university, academic publisher | — | November 26, 1842 |
| University of Oklahoma | public educational institution of the United States, university, public research university | Norman | 1890 |
| University of Oklahoma Press | university press | Norman | — |
| University of Portland | private not-for-profit educational institution, Catholic university | — | 1901 |
| University of Puerto Rico | public university | — | 1903 |
| University of Puget Sound | liberal arts college, Colleges That Change Lives, private not-for-profit educational institution | Tacoma | 1888 |
| University of Richmond | private not-for-profit educational institution, university | Richmond | 1830 |
| University of Rochester | private not-for-profit educational institution, university | Rochester | 1850 |
| University of Saint Joseph | private not-for-profit educational institution, university | — | 1932 |
| University of San Diego | private not-for-profit educational institution, private university | San Diego | 1949 |
| University of South Florida | public educational institution of the United States, open-access publisher, public university | — | 1956 |
| University of Southern Mississippi | public educational institution of the United States, open-access publisher, public university | — | March 30, 1910 |
| University of St. Thomas | private not-for-profit educational institution, private university | Saint Paul | 1885 |
| University of Tampa | private not-for-profit educational institution, university | — | 1931 |
| University of Tennessee | neighborhood, research university, public educational institution of the United States, university, land-grant university, sun grant institution, public university | Knoxville | 1794 |
| University of Texas at El Paso | public educational institution of the United States, public research university | El Paso | 1914 |