| BellSouth | business, enterprise, public company | Atlanta | 1984 |
| Beloit College | liberal arts college, private not-for-profit educational institution | — | 1846 |
| Ben & Jerry's | food brand, business, enterprise, ice cream parlor chain | South Burlington | 1978 |
| Benchmark | business, enterprise | Menlo Park | 1995 |
| Bennington College | college, private not-for-profit educational institution | Bennington | 1932 |
| Bentley Systems | business, public company | Exton | 1984 |
| Berea College | liberal arts college, private not-for-profit educational institution, school | Berea | 1855 |
| Berklee College of Music | private not-for-profit educational institution, college of music, private university | Boston | 1945 |
| Berkshire Hathaway | holding company, business, enterprise, company, public company | Omaha | 1839 |
| Best Buy | business, retail chain, enterprise, public company | Richfield | August 22, 1966 |
| Bethel University | church college, private not-for-profit educational institution, university | — | 1871 |
| Bethesda Softworks | video game publisher, video game developer | Rockville | 1986 |
| Bethlehem Shipbuilding Corporation | shipbuilding company | San Francisco | 1905 |
| Beverly Hills High School | public school, high school | — | 1927 |
| Beverly Hills Hotel | hotel, hotel building | — | 1911 |
| Bicycle Playing Cards | business | Erlanger | — |
| Big Huge Games | video game developer | Timonium | February 2000 |
| Bigelow Aerospace | startup company, privately held company, business | North Las Vegas | 1999 |
| Billboard | periodical, weekly magazine, publishing house, website | New York City | 1894 |
| Bio-Rad Laboratories | business, public company | Hercules | 1952 |
| Biogen | biopharmaceutical company, business, public company | Cambridge | 1978 |
| Biograph Company | film production company | New York City | December 1895 |
| Biola University | church college, private not-for-profit educational institution, seminary, private university | — | 1908 |
| BioRxiv | document repository, preprint server, disciplinary repository | — | November 2013 |
| Bishop Museum | nonprofit organization, museum building, museum, academic publisher | Honolulu | 1889 |
| BitChute | dot-com company, online video platform | Sheridan, Gravesend | January 2017 |
| Bitly | business, URL shortener | New York City | 2008 |
| Black Diamond Equipment | business, enterprise, public company | Holladay | December 1, 1989 |
| Black Mountain College | arts venue, university building, art academy | — | 1933 |
| BlackRock | business, company, public company | New York City | 1988 |
| Blackstone Inc. | asset management company, business, enterprise, public company | New York City | 1985 |
| Blaze Media | news agency, website, video streaming service | Irving | September 12, 2011 |
| Blinding Edge Pictures | film production company, business | Berwyn | 1999 |
| Blockbuster LLC | brand, business, enterprise | Dallas | 1985 |
| Bloomberg L.P. | business, enterprise | New York City, 731 Lexington Avenue | October 1, 1981 |
| Bloomberg News | news agency | New York City | 1990 |
| Blu Products | business | Doral, Paramount | 2009 |
| Blue Sky Studios | animation studio, film production company | Greenwich | February 22, 1987 |
| Bluehost | official website, business, web hosting service | Provo | 2022 |
| Bluepoint Games | video game developer | Austin | March 9, 2006 |
| BlueSky Software | video game developer | California | 1988 |
| Blumhouse Productions | film production company | Los Angeles | 2000 |
| BMC Software | business, enterprise | Houston | 1980 |
| BNSF Railway | railway company, railway network | Fort Worth | September 22, 1995 |
| Bob Jones University | private for-profit educational institution, seminary | — | 1927 |
| Bobcat Company | business | West Fargo | 1947 |
| Boeing | rail vehicle manufacturer, public company, aerospace manufacturer | Chicago | 1934 |
| Boeing Rotorcraft Systems | aerospace manufacturer | United States | 1960 |