| Herman Miller | business, public company | Zeeland | 1923 |
| Hewlett Packard Enterprise | computer manufacturer, software company, business, enterprise | Spring | November 1, 2015 |
| Hi-Rez Studios | video game developer | Alpharetta | 2005 |
| High Moon Studios | video game developer | San Diego | 2001 |
| Hill & Knowlton | public relations agency, business, enterprise | New York City | 1927 |
| Hilton Hotels & Resorts | hotel chain, organization | Texas | 1919 |
| Hofstra University | private not-for-profit educational institution, private university | — | 1935 |
| HOK | architectural firm | St. Louis | 1955 |
| Holland America Line | business, enterprise, cruise line | Seattle | 1873 |
| Hollywood Roosevelt Hotel | hotel | — | 1927 |
| Honda Aircraft Company | aerospace manufacturer | Greensboro | 2006 |
| Honeywell Aerospace | group of companies, business, subsidiary company, enterprise | Phoenix | 1936 |
| Hooters | restaurant chain | Atlanta | 1983 |
| Hooters Air | airline | Myrtle Beach | 2003 |
| Hormel | business, enterprise, company, public company | Austin | 1891 |
| Horseshoe Las Vegas | casino, hotel | — | December 5, 1973 |
| Hotels.com | dot-com company, travel website | — | 1991 |
| House of Blues | restaurant chain, business, chain | Los Angeles | November 26, 1992 |
| Houston Independent School District | school district in the United States | Houston | 1924 |
| Howard University | historically black college or university, private not-for-profit educational institution, school, private university | Washington, D.C. | March 2, 1867 |
| Hudson Motor Car Company | business, automobile manufacturer | Detroit | 1909 |
| Hudson Theatre | Broadway theatre, theatre building, movie theater | — | October 19, 1903 |
| Hughes Aircraft Company | aerospace manufacturer | Culver City, Los Angeles | 1932 |
| Hughes Airwest | airline | San Francisco International Airport | 1968 |
| Hult International Business School | business school, educational institution | — | 1964 |
| Hulu | online film database, website, business, video streaming service | Santa Monica | March 2007 |
| Humana | business, enterprise, public company | Louisville | 1961 |
| Humble Bundle, Inc. | video game publisher, digital book and audiobook distribution platform, digital distribution platform | San Francisco | March 1, 2010 |
| Hupmobile | business, automobile manufacturer | Detroit | 1909 |
| Hurley International | business, subsidiary company | Costa Mesa | 1998 |
| Hy-Vee | supermarket chain, business | West Des Moines | 1930 |
| Hyperloop One | business | Los Angeles | June 2014 |
| Häagen-Dazs | food manufacturer, food brand, trademark, ice cream parlor chain | Oakland | 1961 |
| IBM | software company, multinational corporation, technology company, professional services firm, organization, business, enterprise, public company | Armonk | June 16, 1911 |
| IBM Cloud Video | website, business, online video platform, online community | San Francisco | 2007 |
| Icahn School of Medicine at Mount Sinai | private not-for-profit educational institution, medical school | — | 1963 |
| Icon Comics | publishing house, company | New York City | 2004 |
| Id Software | video game developer, business | Richardson | February 1, 1991 |
| IEEE Computer Society | publishing house, organization | Washington, D.C. | 1963 |
| IFixit | wiki, business | San Luis Obispo | 2003 |
| Ignatius Press | book publisher, publishing house, Catholic organization | San Francisco | 1978 |
| IHeartRadio | dot-com company, internet radio, podcast directory | 32 Avenue of the Americas | — |
| IHOP | restaurant chain | Glendale | July 7, 1958 |
| Illinois Central Railroad | transport company | Chicago | 1851 |
| Illinois Institute of Technology | private not-for-profit educational institution, university | Chicago | 1940 |
| Illinois State University | public educational institution of the United States, university, open-access publisher | — | 1857 |
| Illumina | business, enterprise, company, public company | San Diego | 1998 |
| Illumination | film production company | United States, Santa Monica, Los Angeles, California | January 17, 2007 |