| Jakks Pacific | business, public company | Malibu | 1995 |
| LCG Entertainment, Inc. | video game publisher, video game developer | Malibu | December 27, 2018 |
| Loki Entertainment | video game developer | Tustin | November 9, 1998 |
| Lucasfilm Games | video game publisher, video game developer | San Francisco, Letterman Digital Arts Center | May 1982 |
| MicroProse | video game developer | Hunt Valley | 1982 |
| Mindscape | video game publisher, video game developer | Novato | 1983 |
| Monster Games | video game developer | Northfield | 1996 |
| Naughty Dog | video game developer | Santa Monica | 1984 |
| NetherRealm Studios | video game developer | Chicago | 2010 |
| New World Computing | video game developer | Agoura Hills | 1984 |
| Nightdive Studios | video game publisher, video game developer | Vancouver | 2013 |
| Nintendo Software Technology | video game developer | Redmond | 1998 |
| NovaLogic | video game developer | Agoura Hills | 1985 |
| NStigate Games | video game developer | Marin County | March 1998 |
| Obsidian Entertainment | video game publisher, video game developer, business | Irvine | June 12, 2003 |
| Panic | video game publisher, video game developer, business | Portland, Oregon | — |
| Raven Software | video game developer | Middleton, Madison | 1990 |
| Red Storm Entertainment | video game developer | Cary | 1996 |
| Retro Studios | video game developer | Austin | October 1998 |
| Ripple Effect Studios | video game developer | Los Angeles | 2013 |
| Rockstar New England | video game developer | Andover | 1999 |
| Running with Scissors | video game developer | Tucson | 1996 |
| S2 Games | video game developer | Kalamazoo | 2003 |
| Saber Interactive | video game developer | Fort Lauderdale, Minsk, Sundsvall, Porto, Millburn, Community of Madrid, Saint Petersburg, Florida | 2001 |
| Santa Monica Studio | video game developer | Playa Vista | 1999 |
| Shiny Entertainment | video game developer, business | Laguna Beach, Newport Beach | 1993 |
| Sir-Tech | video game developer | Ogdensburg | 1979 |
| Sony Imagesoft | business | Los Angeles | 1989 |
| Supergiant Games | video game publisher, video game developer | San Jose | 2009 |
| Take-Two Interactive | video game developer, public company | New York City | 1993 |
| Telltale Games | video game publisher, video game developer, business, independent business, enterprise | San Rafael | July 2004 |
| Tengen | video game publisher, video game developer | Milpitas | 1987 |
| The Collective | video game developer | Newport Beach | 1997 |
| The Sims Studio | video game developer | Redwood City | 2006 |
| THQ | video game publisher, video game developer, public company | Agoura Hills, California | 1990 |
| Tilted Mill Entertainment | video game developer | Framingham | 2001 |
| Toys for Bob | video game developer | Novato | 1989 |
| Tripwire Interactive | video game developer | Roswell | 2005 |
| Turn 10 Studios | video game developer | Redmond | 2001 |
| Turtle Beach Systems | business, public company | Valhalla | 1975 |
| Valve Corporation | computer manufacturer, software company, video game publisher, video game developer | Bellevue | 1996 |
| Viz Media, LLC | publishing house, business, company | San Francisco | 1984 |
| Warner Bros. Games | video game publisher, video game developer | Burbank | January 2004 |
| Westwood Studios | video game developer, business | Las Vegas | 1992 |
| ZeniMax Online Studios | video game developer | Hunt Valley | 2007 |
| Zipper Interactive | video game developer | Redmond | 1995 |
| Zombie Studios | video game developer | New-York Tribune | 1994 |