| 2K Sports | video game publisher | Novato | January 25, 2005 |
| 3D Realms | video game developer | Garland | 1994 |
| Activision | video game publisher, video game developer, subsidiary company | Santa Monica | October 1, 1979 |
| Adscape | business | San Francisco | 2006 |
| Aeria Games | business | Berlin | 2006 |
| Airtight Games | video game developer | Redmond | 2004 |
| Amaze Entertainment | video game developer, business | Kirkland | 1997 |
| Annapurna Interactive | video game publisher, company | Los Angeles | December 1, 2016 |
| Atari Corporation | video game publisher, technology company, business | Sunnyvale | July 2, 1984 |
| Atari, Inc. | video game publisher, video game developer | New York City | February 1993 |
| Atari, Inc. | video game publisher | New York City | February 1993 |
| Bethesda Softworks | video game publisher, video game developer | Rockville | 1986 |
| Big Huge Games | video game developer | Timonium | February 2000 |
| Bluepoint Games | video game developer | Austin | March 9, 2006 |
| BlueSky Software | video game developer | California | 1988 |
| Cinematronics | video game developer | El Cajon | 1975 |
| Cinemaware | video game publisher, video game developer | Burlingame | 1986 |
| Crave Entertainment | video game developer | Newport Beach | 1997 |
| Cryptic Studios | video game developer | Los Gatos | June 2000 |
| Daybreak Game Company | video game developer | San Diego | 1995 |
| Digital Anvil | video game developer | Austin | 1996 |
| Disney Interactive Studios | video game developer | Glendale | December 5, 1994 |
| EA Mobile | video game developer | Los Angeles | 2004 |
| EA Sports | business | Burnaby | 1991 |
| Ensemble Studios | video game developer | Dallas | 1995 |
| Epyx | video game publisher, video game developer, business, enterprise | San Francisco | 1978 |
| Exidy | business | Sunnyvale | 1974 |
| Firaxis Games | video game developer | Sparks | 1996 |
| Frog City Software | video game developer | San Francisco | 1995 |
| Gathering of Developers | video game publisher, business | Texas | January 1998 |
| Gearbox Software | video game publisher, video game developer | Frisco | January 1999 |
| Giant Sparrow | video game developer, business, enterprise | Santa Monica | March 22, 2009 |
| Glu Mobile | video game publisher, video game developer, business, enterprise, public company | San Francisco | 2005 |
| Griptonite Games | video game developer | Kirkland | 1994 |
| Halo Studios | video game developer | Redmond | 2009 |
| Hi-Rez Studios | video game developer | Alpharetta | 2005 |
| High Moon Studios | video game developer | San Diego | 2001 |
| Humble Bundle, Inc. | video game publisher, digital book and audiobook distribution platform, digital distribution platform | San Francisco | March 1, 2010 |
| Id Software | video game developer, business | Richardson | February 1, 1991 |
| Imagic | video game publisher, video game developer | Los Gatos | 1981 |
| Incognito Entertainment | video game developer | Salt Lake City | May 1999 |
| Indie Built | video game developer | Salt Lake City | 1983 |
| Infinity Ward | video game developer | Woodland Hills | 2002 |
| Infocom | video game publisher, video game developer, business | Cambridge | June 22, 1979 |
| Interplay Entertainment | video game publisher, video game developer | Beverly Hills | October 1983 |
| Iron Galaxy Studios | video game publisher, video game developer | Chicago | 2008 |
| Iron Lore Entertainment | video game developer | Boston | October 2000 |
| Irrational Games | video game developer | Boston | 1997 |