| Aeronca | aerospace manufacturer | Cincinnati, Middletown | 1928 |
| Air Tractor | business | Olney | 1973 |
| Alliant Techsystems | enterprise, public company, aerospace manufacturer | Arlington County | 1990 |
| Armadillo Aerospace | privately held company | Mesquite | 2000 |
| Bigelow Aerospace | startup company, privately held company, business | North Las Vegas | 1999 |
| Boeing | rail vehicle manufacturer, public company, aerospace manufacturer | Chicago | 1934 |
| Boeing Rotorcraft Systems | aerospace manufacturer | United States | 1960 |
| Brewster Aeronautical Corporation | aerospace manufacturer | — | 1932 |
| Cirrus Aircraft Corporation | aerospace manufacturer | Duluth | 1984 |
| Collins Aerospace | defense contractor, aerospace manufacturer | Charlotte | 2018 |
| Curtiss-Wright | holding company, business, public company, aerospace manufacturer | Charlotte | 1929 |
| Deep Space Industries | business, enterprise | Mountain View | January 22, 2013 |
| Enstrom Helicopter Corporation | business | Menominee | 1959 |
| Firefly Aerospace | launch service provider, business | Cedar Park | 2014 |
| Ford Aerospace | business | Milpitas | 1956 |
| General Atomics Aeronautical Systems | subsidiary company, enterprise | Poway | 1993 |
| General Dynamics | business, public company | Reston | February 21, 1952 |
| Harris Corporation | former entity, business, public company | Melbourne | 1955 |
| Honeywell Aerospace | group of companies, business, subsidiary company, enterprise | Phoenix | 1936 |
| Hughes Aircraft Company | aerospace manufacturer | Culver City, Los Angeles | 1932 |
| Lockheed Martin | defense contractor, public company | Bethesda | 1995 |
| Lycoming | business | Williamsport | 1845 |
| Martin Marietta | business, enterprise | Bethesda | 1961 |
| Masten Space Systems | business | Mojave | 2004 |
| McDonnell Aircraft Corporation | aerospace manufacturer | St. Louis | July 6, 1939 |
| McDonnell Douglas | former entity, defense contractor, aerospace manufacturer | St. Louis | 1967 |
| Northrop Grumman Corporation | defense contractor, public company, aerospace manufacturer | Falls Church | 1994 |
| Orbital ATK | launch service provider, former entity, defense contractor, aerospace manufacturer | Dulles | February 9, 2015 |
| Orbital Sciences Corporation | launch service provider, enterprise, public company, aerospace manufacturer | Dulles | 1982 |
| Pratt & Whitney | business | East Hartford | 1925 |
| Robinson Helicopter Company | business, enterprise | Zamperini Field | 1973 |
| Rockwell Collins | defense contractor, business, public company, aerospace manufacturer | Cedar Rapids | 1933 |
| RTX | defense contractor, business, public company | Arlington County | April 3, 2020 |
| Ryan Aeronautical | business | San Diego | 1934 |
| Stratolaunch Systems | business, enterprise | Montgomery, Seattle | 2011 |
| Swift Engineering | business, enterprise, aerospace manufacturer | San Clemente | 1983 |
| TRW Inc. | business, enterprise | Euclid | 1901 |
| Waco | business | Troy | 1919 |
| Williams International | business, enterprise | Commerce Township | 1954 |