| American Bible Society | Bible society, nonprofit organization | May 11, 1816 |
| American Line | transport company | 1871 |
| Bank of North America | bank, central bank | 1781 |
| Chikara | business, professional wrestling promotion | 2002 |
| Comcast | telecommunications company, business, enterprise, public company | June 28, 1963 |
| Conrail | railway company | April 1, 1976 |
| Eckert–Mauchly Computer Corporation | business | 1948 |
| Evolve | business | 2009 |
| Extreme Championship Wrestling | media franchise, business | April 25, 1992 |
| Lubin Manufacturing Company | film production company | 1902 |
| Pennsylvania Railroad | railway company, business | April 13, 1846 |
| Sports Reference | business | December 3, 2007 |
| Thomas Jefferson University | private not-for-profit educational institution, university | 1824 |
| William Cramp & Sons | shipbuilding company | 1830 |
| Young & Rubicam | advertising agency | 1923 |