| Abbott-Detroit | automobile manufacturer | 1909 |
| American Axle | business, enterprise, public company | 1994 |
| Cadillac | automobile manufacturer | 1902 |
| Chevrolet | car brand, automobile manufacturer | November 3, 1911 |
| Gale | publishing house | 1954 |
| Hudson Motor Car Company | business, automobile manufacturer | 1909 |
| Hupmobile | business, automobile manufacturer | 1909 |
| Rivian Automotive | business, enterprise, automobile manufacturer, public company | June 2009 |