| American Schools of Oriental Research | nonprofit organization, learned society, academic publisher | 1900 |
| American Tower Corporation | business, enterprise, public company | 1995 |
| Arctic Coal Company | mining company | 1906 |
| Au Bon Pain | business | 1978 |
| Bain & Company | management consulting company | 1973 |
| Berklee College of Music | private not-for-profit educational institution, college of music, private university | 1945 |
| Boston Beer Company | brewery, public company | 1985 |
| Converse | brand, business | 1910 |
| Da Capo Press | publishing house | 1964 |
| Dynatrace | software company, public company | February 2, 2005 |
| Emerson College | private not-for-profit educational institution, university | 1880 |
| Federal Home Loan Banks | business, credit institution | 1932 |
| Fenway Sports Group | business, enterprise | 2001 |
| Fidelity Investments | business, enterprise | 1946 |
| GoTo | software company, enterprise, public company | 2003 |
| Institute of Contemporary Art, Boston | art gallery, nonprofit organization, art museum | 1936 |
| Iron Lore Entertainment | video game developer | October 2000 |
| Irrational Games | video game developer | 1997 |
| John Hancock Insurance | business | 1862 |
| Liberty Mutual Insurance | business, enterprise | 1912 |
| MFS Investment Management | business | 1924 |
| Parametric Technology Corporation | business, enterprise, public company | May 1985 |
| Semrush | brand, business, public company | August 3, 2008 |
| University of Massachusetts | state university system | 1863 |
| Wellington Management Company | business, enterprise | 1928 |
| WHOOP | business | — |
| Ximian | business, enterprise | October 19, 1999 |